Science Junkie
Whole brain cellular-level activity mapping once a second
Neuroscientists at Howard Hughes Medical Institute have mapped the activity of nearly all the neurons in a vertebrate brain at cellular resolution, with signficant implications for neuroscience research. The researchers used high-speed light sheet microscopy to image the activity of 80% of the neurons in the brain (which is composed of ~100,000 neurons) of a fish larva at 0.8 Hz (an image every 1.3 seconds), with single-cell resolution.
This represents the first technology that achieves whole brain imaging of a vertebrate brain at cellular resolution with speeds that approximate neural activity patterns and behavior, as Nature Methods methagora blog noted. The authors saw correlated activity patterns at the cellular level that spanned large areas of the brain — pointing to the existence of broadly distributed functional circuits.The next steps will be to determine the causal role that these circuits play in behavior — something that will require improvements in the methods for 3D optogenetics, the blog said. Obtaining the detailed anatomical map of these circuits will also be key to understand the brain’s organization at its deepest level.
Sources: kurzweilai.net - nature.com

Whole brain cellular-level activity mapping once a second

Neuroscientists at Howard Hughes Medical Institute have mapped the activity of nearly all the neurons in a vertebrate brain at cellular resolution, with signficant implications for neuroscience research. The researchers used high-speed light sheet microscopy to image the activity of 80% of the neurons in the brain (which is composed of ~100,000 neurons) of a fish larva at 0.8 Hz (an image every 1.3 seconds), with single-cell resolution.


This represents the first technology that achieves whole brain imaging of a vertebrate brain at cellular resolution with speeds that approximate neural activity patterns and behavior, as Nature Methods methagora blog noted. The authors saw correlated activity patterns at the cellular level that spanned large areas of the brain — pointing to the existence of broadly distributed functional circuits.

The next steps will be to determine the causal role that these circuits play in behavior — something that will require improvements in the methods for 3D optogenetics, the blog said. Obtaining the detailed anatomical map of these circuits will also be key to understand the brain’s organization at its deepest level.

Sources: kurzweilai.net - nature.com







  1. strong-medicine reblogged this from rmedicine
  2. sandyman21 reblogged this from syno-shen
  3. syno-shen reblogged this from cuddlebunnyme
  4. cuddlebunnyme reblogged this from neuromorphogenesis
  5. purpleclosetnerd reblogged this from articulomortis
  6. aspiringdoctorsclub reblogged this from rmedicine
  7. liminalitea reblogged this from coolbeebsie
  8. coolbeebsie reblogged this from articulomortis
  9. bioehoes reblogged this from articulomortis
  10. jaciemarieporvida reblogged this from science-junkie
  11. rejectwolf reblogged this from unabellaanima
  12. imanomalous reblogged this from unabellaanima
  13. unabellaanima reblogged this from sacrificial-lambs
  14. exclusive-delight reblogged this from 0hi
  15. thearlequinsscars reblogged this from wurmiv
  16. wurmiv reblogged this from articulomortis
  17. alexthesurgeon reblogged this from science-junkie
  18. dyanlaurel reblogged this from science-junkie
  19. kexoathe reblogged this from science-junkie
  20. medbeat reblogged this from articulomortis
  21. a-song-for-lya reblogged this from articulomortis
  22. verowalls reblogged this from articulomortis
  23. mutedimagination reblogged this from articulomortis
  24. sarahlovesa7x reblogged this from science-junkie
  25. kaylastargazer reblogged this from articulomortis
  26. rmedicine reblogged this from articulomortis
  27. rudegirl44 reblogged this from articulomortis
  28. lifebyosmosis reblogged this from scinerds and added:
    whole brain cellular-level activity mapping once a second
  29. kinda-real-awkward reblogged this from articulomortis